I-TASSER是一款用于预测蛋白质结构和功能的工具，网站链接：https://zhanglab.ccmb.med.umich.edu/I-TASSER/

具体描述如下：

I-TASSER (Iterative Threading ASSEmbly Refinement) is a hierarchical approach to protein structure and function prediction. It first identifies structural templates from the PDB by multiple threading approach , with full-length atomic models constructed by iterative template fragment assembly simulations. Function insights of the target are then derived by threading the 3D models through protein function database . I-TASSER (as 'Zhang-Server') was ranked as the No 1 server for protein structure prediction in recent community-wide , , , , , and  experiments. It was also ranked as the best for function prediction in . The server is in active development with the goal to provide the most accurate structural and function predictions using state-of-the-art algorithms. Please report problems and questions at  and our developers will answer the questions.

使用步骤很简单，先把要预测的蛋白质的氨基酸序列黏贴在框框里，如下图红色框框所示：

填写邮箱，密码（如果之前没注册过的话，需要点击password那栏的here进行注册，注册完邮箱会发送密码），ID可以随意写，最后，点击“Run I-TASSER”。1~2天邮件会收到结果通知。